Senior Principal Scientist (all genders) - Thrombosis

Senior Principal Scientist (all genders) - Thrombosis Location: Germany, North Rhine Westphalia, Wuppertal-Aprath As a Senior Principal Scientist (m/f/d), you will play a pivotal role in representing CVRI Research on global clinical‑phase Thrombosis programs. You will collaborate closely with translational, clinical, and regulatory functions to develop and execute research plans that inform dose selection, elucidate mechanisms of action, and strengthen the target‑disease link. Your efforts will maximize value and support life‑cycle management for late‑stage assets. You will provide deep scientific expertise in pre‑clinical research pharmacology, particularly in the areas of stroke, thrombosis, and neuroprotection, contributing to strategic research and development activities. Responsibilities Represent CVRI Research on global clinical‑phase Thrombosis programs, collaborating with translational, clinical, and regulatory functions Develop and execute research plans to inform dose selection and mechanisms of action, strengthening target‑disease link and supporting life‑cycle management for late‑stage assets Provide scientific and strategic expertise in pre‑clinical research pharmacology involving stroke and thrombosis; establish and maintain close connections to key opinion leaders in this area Design and supervise in‑vitro, ex‑vivo and/or in‑vivo studies to support target rationale and therapeutic candidate characterization Generate key documentation and presentations for internal review and regulatory submissions Ensure compliance with all HSE, documentation, and Good Research Practice guidelines Coach and guide research associates and junior scientists within a matrix organization Collaborate with colleagues and external partners to assess external targets and identify opportunities for collaboration or innovation Qualifications Ph.D. in a Biological or Medical Science Deep expertise in Thrombosis & Hemostasis Research with a proven track record of scientific leadership and publication in this field. Knowledge of key patho‑mechanisms relevant to stroke and neuroprotection would be highly advantageous Multi‑year experience in drug discovery and development, ideally in a pharmaceutical or biotech setting Extensive experience and hands‑on skills in designing in‑vitro, ex‑vivo, and/or in‑vivo models for relevant patho‑mechanisms in this field (e.g. coagulation, fibrinolysis, platelet activation, clot composition) Demonstrated experience in strategic planning and project leadership Excellent communication and interpersonal skills for cross‑functional collaboration Ability to manage changes in a fast‑paced environment Passion for science and urgency to discover new medicines for patient benefit Fluency in English, both written and spoken Benefits Our benefits package is flexible, appreciative, and tailored to your lifestyle, because:What matters to you, matters to us! We ensure your financial stability with a competitive salary between €109,800 and €167,300 per year (full‑time) plus a variable component. Your compensation is based on your qualifications, skills, and professional experience Whether it’s hybrid work models or part‑time arrangements: Whenever possible, you will have the flexibility to work how, when and where it is best for you Your family is a top priority. We offer loving company daycare centers at multiple locations, support in finding childcare, time off for the care of elderly or dependent family members, summer camps for children, and much more We support your professional growth by providing access to learning and development opportunities, training programs through the Bayer Learning Academy, development dialogues, coaching and mentoring programs We promote health awareness and opportunities for self‑care through various measures, such as free health checks with the company doctor We embed diversity by providing an inclusive work environment in which you are welcomed, supported, and encouraged to bring your whole self to work Bayer welcomes applications from all individuals, regardless of national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, orientation, gender identity, gender expression or any criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.